CENTRAL HEMODYNAMICS AND OXYGEN TRANSPORT IN PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME CAUSED BY COVID-19 AND THEIR IMPACT ON THE COURSE AND OUTCOMES OF THE DISEASE

The aim. Determine hemodynamic status and its impact on oxygen transport, frequency of adverse events outcomes in patients with severe SARS-CoV-2 associated acute respiratory distress syndrome (ARDS).
 Materials methods. A single-center prospective comparative study was conducted 29 enrolled over the period July—October 2020 who suffered a course coronavirus disease bilateral pneumonia ARDS. Based estimated cardiac index (CI), were allocated to two groups: Group 1 included 14 ARDS CI 1.9 [1.5–2.5] L/min/m2, whereas 2 15 4.2 [3.2–8.1] L/min/m2 (p=0.001). Patient`s intensive care regulated by relevant orders Ministry Health Ukraine. Statistical analysis results carried out using Statistica 10 software. significance parameters assessed non-parametric Wilcoxon criterion. Results considered significant at p values <0.05. Data are presented as M [25–75]. Relative risk (RR) odds ratio (OR) calculated.
 Results. is transport disorders that increase hypovolemia. Despite delivery group normal high tissue extraction remained, which may be sign development mitochondrial distress.
 Conclusions. Patients admitted ICU COVID-19 state hypovolemia require individual assessment appointment infusion therapy. Increased decreased rate statistically decrease mortality